Cargando…

The Cellular Prion Protein: A Promising Therapeutic Target for Cancer

Studies on the cellular prion protein (PrP(C)) have been actively conducted because misfolded PrP(C) is known to cause transmissible spongiform encephalopathies or prion disease. PrP(C) is a glycophosphatidylinositol-anchored cell surface glycoprotein that has been reported to affect several cellula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Go, Gyeongyun, Lee, Sang Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730109/ https://www.ncbi.nlm.nih.gov/pubmed/33276687 http://dx.doi.org/10.3390/ijms21239208

Ejemplares similares

Harnessing the Physiological Functions of Cellular Prion Protein in the Kidneys: Applications for Treating Renal Diseases
por: Yoon, Sungtae, et al.
Publicado: (2021)

Prion Protein of Extracellular Vesicle Regulates the Progression of Colorectal Cancer
por: Yun, Chul-Won, et al.
Publicado: (2021)

The Dual Role of Autophagy in Cancer Development and a Therapeutic Strategy for Cancer by Targeting Autophagy
por: Yun, Chul Won, et al.
Publicado: (2020)

Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis
por: Han, Yong-Seok, et al.
Publicado: (2020)

Correction: Yun et al. Prion Protein of Extracellular Vesicle Regulates the Progression of Colorectal Cancer. Cancers 2021, 13, 2144
por: Yun, Chul-Won, et al.
Publicado: (2021)

Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target?
por: Yousaf, Saba, et al.
Publicado: (2022)

Pharmacological Agents Targeting the Cellular Prion Protein
por: Barreca, Maria Letizia, et al.
Publicado: (2018)

The Role of Cellular Prion Protein in Cancer Biology: A Potential Therapeutic Target
por: Ding, Manqiu, et al.
Publicado: (2021)

The Cellular Prion Protein and the Hallmarks of Cancer
por: Mouillet-Richard, Sophie, et al.
Publicado: (2021)

Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells
por: Han, Yong-Seok, et al.
Publicado: (2016)

α-Cleavage of cellular prion protein
por: Liang, Jingjing, et al.
Publicado: (2012)

Role of hypoxia-mediated cellular prion protein functional change in stem cells and potential application in angiogenesis
por: Yun, Seung Pil, et al.
Publicado: (2017)

The Role of Cellular Prion Protein in Promoting Stemness and Differentiation in Cancer
por: Ryskalin, Larisa, et al.
Publicado: (2021)

Cellular Prion Protein: From Physiology to Pathology
por: Yusa, Sei-ichi, et al.
Publicado: (2012)

The biological function of the cellular prion protein: an update
por: Wulf, Marie-Angela, et al.
Publicado: (2017)

Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway
por: Lee, Jun Hee, et al.
Publicado: (2018)

PrP(C) Aptamer Conjugated–Gold Nanoparticles for Targeted Delivery of Doxorubicin to Colorectal Cancer Cells
por: Go, Gyeongyun, et al.
Publicado: (2021)

Understanding and exploiting interactions between cellular proteostasis pathways and infectious prion proteins for therapeutic benefit
por: Yakubu, Unekwu M., et al.
Publicado: (2020)

Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions
por: Mays, Charles E., et al.
Publicado: (2022)

A New Take on Prion Protein Dynamics in Cellular Trafficking
por: Alves, Rodrigo Nunes, et al.
Publicado: (2020)

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
por: Chatterjee, Suman, et al.
Publicado: (2017)

The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain
por: Gavín, Rosalina, et al.
Publicado: (2020)

Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression
por: Han, Yong Seok, et al.
Publicado: (2018)

Prion protein signaling as therapeutic target in human tumors
por: Martins, Vilma Regina
Publicado: (2013)

Tauroursodeoxycholic acid reduces ER stress by regulating of Akt-dependent cellular prion protein
por: Yoon, Yeo Min, et al.
Publicado: (2016)

Physiological Functions of the Cellular Prion Protein
por: Castle, Andrew R., et al.
Publicado: (2017)

Neurotoxicity of Prion Peptides Mimicking the Central Domain of the Cellular Prion Protein
por: Vilches, Silvia, et al.
Publicado: (2013)

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises
por: McAlary, Luke, et al.
Publicado: (2020)

RNA-binding protein 39: a promising therapeutic target for cancer
por: Xu, Caipeng, et al.
Publicado: (2021)

Cellular Aspects of Prion Replication In Vitro
por: Grassmann, Andrea, et al.
Publicado: (2013)

Evaluation of Infective Property of Recombinant Prion Protein Amyloids in Cultured Cells Overexpressing Cellular Prion Protein
por: Kim, Dae-Hwan, et al.
Publicado: (2014)

Dual role of cellular prion protein in normal host and Alzheimer’s disease
por: ONODERA, Takashi
Publicado: (2017)

Targeting KRAS in Cancer: Promising Therapeutic Strategies
por: Mustachio, Lisa Maria, et al.
Publicado: (2021)

Regulation of RhoA activity by the cellular prion protein
por: Kim, Hee-Jun, et al.
Publicado: (2017)

miRNA: A Promising Therapeutic Target in Cancer
por: Menon, Amrutha, et al.
Publicado: (2022)

Metabolism of minor isoforms of prion proteins: Cytosolic prion protein and transmembrane prion protein
por: Song, Zhiqi, et al.
Publicado: (2013)

Cellular Prion Protein (PrPc): Putative Interacting Partners and Consequences of the Interaction
por: Miranzadeh Mahabadi, Hajar, et al.
Publicado: (2020)

On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseases
por: Legname, Giuseppe, et al.
Publicado: (2020)

Roles of the cellular prion protein in the regulation of cell-cell junctions and barrier function
por: Petit, Constance S.V., et al.
Publicado: (2013)

Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells †
por: Thellung, Stefano, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fan9pso4411nn62gipe5ukb639