Synthesis and in Silico Modelling of the Potential Dual Mechanistic Activity of Small Cationic Peptides Potentiating the Antibiotic Novobiocin against Susceptible and Multi-Drug Resistant Escherichia coli

Cationic antimicrobial peptides have attracted interest, both as antimicrobial agents and for their ability to increase cell permeability to potentiate other antibiotics. However, toxicity to mammalian cells and complexity have hindered development for clinical use. We present the design and synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Passarini, Ilaria, de Resende, Pedro Ernesto, Soares, Sarah, Tahmasi, Tadeh, Stapleton, Paul, Malkinson, John, Zloh, Mire, Rossiter, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730182/
https://www.ncbi.nlm.nih.gov/pubmed/33266278
http://dx.doi.org/10.3390/ijms21239134

Ejemplares similares

Ejemplares similares