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Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

The nonreceptor tyrosine TEC kinases are key regulators of the immune system and play a crucial role in the pathogenesis of diverse hematological malignancies. In contrast to the substantial efforts in inhibitor development for Bruton’s tyrosine kinase (BTK), specific inhibitors of the other TEC kin...

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Detalles Bibliográficos
Autores principales:	Forster, Michael, Liang, Xiaojun Julia, Schröder, Martin, Gerstenecker, Stefan, Chaikuad, Apirat, Knapp, Stefan, Laufer, Stefan, Gehringer, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730235/ https://www.ncbi.nlm.nih.gov/pubmed/33291717 http://dx.doi.org/10.3390/ijms21239269

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