On the Single-Crystal Structure of Tenofovir Alafenamide Mono-Fumarate: A Metastable Phase Featuring a Mixture of Co-Crystal and Salt

Tenofovir alafenamide (TAF) is a prodrug of tenofovir as a potent nucleotide reverse transcriptase inhibitor. It serves as the key component of Genvoya(®) for the first-line treatment of human immunodeficiency virus infection (HIV) and is the active component of Vemlidy(®) for the treatment of chron...

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Detalles Bibliográficos
Autores principales: Wang, Jian-Wei, Liu, Lu, Yu, Ka-Xi, Bai, Hong-Zhen, Zhou, Jun, Zhang, Wen-Hua, Hu, Xiurong, Tang, Guping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730268/
https://www.ncbi.nlm.nih.gov/pubmed/33287166
http://dx.doi.org/10.3390/ijms21239213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730268/
https://www.ncbi.nlm.nih.gov/pubmed/33287166
http://dx.doi.org/10.3390/ijms21239213

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