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On the Single-Crystal Structure of Tenofovir Alafenamide Mono-Fumarate: A Metastable Phase Featuring a Mixture of Co-Crystal and Salt
Tenofovir alafenamide (TAF) is a prodrug of tenofovir as a potent nucleotide reverse transcriptase inhibitor. It serves as the key component of Genvoya(®) for the first-line treatment of human immunodeficiency virus infection (HIV) and is the active component of Vemlidy(®) for the treatment of chron...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730268/ https://www.ncbi.nlm.nih.gov/pubmed/33287166 http://dx.doi.org/10.3390/ijms21239213 |