Cargando…

Carnosine to Combat Novel Coronavirus (nCoV): Molecular Docking and Modeling to Cocrystallized Host Angiotensin-Converting Enzyme 2 (ACE2) and Viral Spike Protein

Aims: Angiotensin-converting enzyme 2 (ACE2) plays an important role in the entry of coronaviruses into host cells. The current paper described how carnosine, a naturally occurring supplement, can be an effective drug candidate for coronavirus disease (COVID-19) on the basis of molecular docking and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saadah, Loai M., Deiab, Ghina’a I. Abu, Al-Balas, Qosay, Basheti, Iman A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730390/ https://www.ncbi.nlm.nih.gov/pubmed/33260592 http://dx.doi.org/10.3390/molecules25235605

Ejemplares similares

Computational medicinal chemistry role in clinical pharmacy education: Ingavirin for coronavirus disease 2019 (COVID-19) discovery model
por: Saadah, Loai M, et al.
Publicado: (2022)

Docking Studies of Methylthiomorpholin Phenols (LQM300 Series) with Angiotensin-Converting Enzyme (ACE)
por: Vázquez-Valadez, Víctor H., et al.
Publicado: (2013)

COVID-19 pandemic: an overview of epidemiology, parthenogenesis, diagnostics and potential vaccines and therapeutics
por: Amawi, Haneen, et al.
Publicado: (2020)

Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling
por: Clarke, Nicola E., et al.
Publicado: (2012)

Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome
por: Gómez, Juan, et al.
Publicado: (2020)

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae
por: Burnham, Susan, et al.
Publicado: (2005)

Angiotensin converting enzyme gene polymorphism and influence of ACE inhibition
por: Arman, Q.
Publicado: (2010)

Considerations for Docking of Selective Angiotensin-Converting Enzyme Inhibitors
por: Caballero, Julio
Publicado: (2020)

In silico screening of dicarboxylic acids for cocrystallization with phenylpiperazine derivatives based on both cocrystallization propensity and solubility advantage
por: Cysewski, Piotr
Publicado: (2017)

Manipulating angiotensin metabolism with angiotensin converting enzyme 2 (ACE2) in heart failure
por: Patel, Vaibhav B., et al.
Publicado: (2012)

Angiotensin I-Converting Enzyme (ACE) Inhibition and Molecular Docking Study of Meroterpenoids Isolated from Brown Alga, Sargassum macrocarpum
por: Ko, Seok-Chun, et al.
Publicado: (2023)

Exploring the cocrystallization potential of urea and benzamide
por: Cysewski, Piotr, et al.
Publicado: (2016)

Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization
por: Al-Kazemi, Reham, et al.
Publicado: (2019)

Tuning the Pharmacokinetic Performance of Quercetin by Cocrystallization
por: Haskins, Molly M., et al.
Publicado: (2023)

The Race for ACE: Targeting Angiotensin-Converting Enzymes (ACE) in SARS-CoV-2 Infection
por: Schieffer, Elisabeth, et al.
Publicado: (2022)

Three key proteases – angiotensin-I-converting enzyme (ACE), ACE2 and renin – within and beyond the renin-angiotensin system
por: Guang, Cuie, et al.
Publicado: (2012)

The Insertion/Deletion Polymorphism of the Angiotensin Converting Enzyme (ACE) in Parkinson’s Disease
por: Papapetropoulos, Spiridon, et al.
Publicado: (2008)

Angiotensin-I-Converting Enzyme (ACE)-Inhibitory Peptides from Plants
por: Daskaya-Dikmen, Ceren, et al.
Publicado: (2017)

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
por: Ni, Wentao, et al.
Publicado: (2020)

Covid-19 and the angiotensin-converting enzyme (ACE2): Areas for research
por: Omar, Michael Brandon
Publicado: (2020)

Characterization of Angiotensin Converting Enzyme-2 (ACE2) in Human Urine
por: Lew, Rebecca A., et al.
Publicado: (2006)

Angiotensin Converting Enzyme (ACE): A Marker for Personalized Feedback on Dieting
por: Tejpal, Shilpa, et al.
Publicado: (2020)

Purification and characterization of angiotensin-converting enzyme (ACE) from sheep lung
por: Aydin, Fatih, et al.
Publicado: (2021)

Investigation of angiotensin-I-converting enzyme (ACE) inhibitory tri-peptides: a combination of 3D-QSAR and molecular docking simulations
por: Wang, Fangfang, et al.
Publicado: (2020)

Identification of novel inhibitors of angiotensin-converting enzyme 2 (ACE-2) receptor from Urtica dioica to combat coronavirus disease 2019 (COVID-19)
por: Upreti, Shobha, et al.
Publicado: (2021)

Competitive cocrystallization and its application in the separation of flavonoids
por: Xia, Yanming, et al.
Publicado: (2021)

Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization"
por: Emami, Shahram, et al.
Publicado: (2021)

Cocrystallization of Antifungal Compounds Mediated by Halogen Bonding
por: Benito, Mónica, et al.
Publicado: (2023)

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2
por: Clayton, Daniel, et al.
Publicado: (2015)

DNA Methylation Analysis of the Angiotensin Converting Enzyme (ACE) Gene in Major Depression
por: Zill, Peter, et al.
Publicado: (2012)

Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span
por: Kumar, Sandeep, et al.
Publicado: (2016)

Angiotensin-converting enzyme 2 (ACE2) is upregulated in Alzheimer’s disease brain
por: Ding, Qiyue, et al.
Publicado: (2020)

Measurement of Angiotensin Converting Enzyme 2 Activity in Biological Fluid (ACE2)
por: Xiao, Fengxia, et al.
Publicado: (2017)

Angiotensin Converting Enzyme-2 (ACE-2) role in disease and future in research
por: Abdul-Hafez, Amal, et al.
Publicado: (2021)

Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19
por: Kuba, Keiji, et al.
Publicado: (2021)

Identification and characterisation of the angiotensin converting enzyme-3 (ACE3) gene: a novel mammalian homologue of ACE
por: Rella, Monika, et al.
Publicado: (2007)

Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease
por: Tikellis, Chris, et al.
Publicado: (2012)

New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) I: Endogenous Angiotensin Converting Enzyme (ACE) Inhibition
por: Fagyas, Miklós, et al.
Publicado: (2014)

Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney
por: Jiang, Xiao, et al.
Publicado: (2020)

Inhibition kinetics, molecular docking, and stability studies of the effect of papain-generated peptides from palm kernel cake proteins on angiotensin-converting enzyme (ACE)
por: Zarei, Mohammad, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6kfp45i1iuple2n7eqt7etvduc