Cargando…

Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model

In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hasegawa, Tomoko, Ikeda, Hanako O., Iwai, Sachiko, Sasaoka, Norio, Kakizuka, Akira, Tsujikawa, Akitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730440/ https://www.ncbi.nlm.nih.gov/pubmed/33303850 http://dx.doi.org/10.1038/s41598-020-78731-2

Ejemplares similares

Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Retinal ganglion cell protection by hop-flower extract as a novel neuroprotective strategy for glaucoma
por: Hasegawa, Tomoko, et al.
Publicado: (2021)

Long-Term Oral Administration of Hop Flower Extracts Mitigates Alzheimer Phenotypes in Mice
por: Sasaoka, Norio, et al.
Publicado: (2014)

Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma
por: Hasegawa, Tomoko, et al.
Publicado: (2018)

Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage
por: Kusaka, Mami, et al.
Publicado: (2022)

KUS121, an ATP regulator, mitigates chorioretinal pathologies in animal models of age-related macular degeneration
por: Muraoka, Yuki, et al.
Publicado: (2018)

Branched Chain Amino Acids Promote ATP Production Via Translocation of Glucose Transporters
por: Iwai, Sachiko, et al.
Publicado: (2022)

KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats
por: Iwai, Sachiko, et al.
Publicado: (2021)

Neuroprotective effects of VCP modulators in mouse models of glaucoma
por: Nakano, Noriko, et al.
Publicado: (2016)

KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress
por: Hata, Masayuki, et al.
Publicado: (2017)

Expansion of retinal nerve fiber bundle narrowing in glaucoma: An adaptive optics scanning laser ophthalmoscopy study
por: Hasegawa, Tomoko, et al.
Publicado: (2020)

Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
por: Hasegawa, Tomoko, et al.
Publicado: (2016)

Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa
por: Ikeda, Hanako Ohashi, et al.
Publicado: (2014)

Influence of Trabeculectomy with Mitomycin C on Longitudinal Changes in the Visual Field in Glaucoma Patients with High Myopia
por: Yamagata, Yutaro, et al.
Publicado: (2023)

Evaluation of Structure-Function Relationships in Longitudinal Changes of Glaucoma using the Spectralis OCT Follow-Up Mode
por: Suda, Kenji, et al.
Publicado: (2018)

Estimating the rate of retinal ganglion cell loss to detect glaucoma progression: An observational cohort study
por: Hirooka, Kazuyuki, et al.
Publicado: (2016)

Long-term efficacy and safety of anti-VEGF therapy in retinitis pigmentosa: a case report
por: Miyata, Manabu, et al.
Publicado: (2018)

Wavelength of light and photophobia in inherited retinal dystrophy
por: Otsuka, Yuki, et al.
Publicado: (2020)

A Trace Amount of Galactose, a Major Component of Milk Sugar, Allows Maturation of Glycoproteins during Sugar Starvation
por: Sasaoka, Norio, et al.
Publicado: (2018)

Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial
por: Ikeda, Hanako Ohashi, et al.
Publicado: (2020)

Detection Sensitivity of Retinitis Pigmentosa Progression Using Static Perimetry and Optical Coherence Tomography
por: Hasegawa, Tomoko, et al.
Publicado: (2021)

Relationship between Ocular Deviation and Visual Function in Retinitis Pigmentosa
por: Miyata, Manabu, et al.
Publicado: (2018)

ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson's Disease
por: Nakano, Masaki, et al.
Publicado: (2017)

Clinical Characteristics, Differential Diagnosis and Genetic Analysis of Concentric Retinitis Pigmentosa
por: Nakahara, Mei, et al.
Publicado: (2021)

Bax Contributes to Retinal Ganglion Cell Dendritic Degeneration During Glaucoma
por: Risner, Michael L., et al.
Publicado: (2022)

Baerveldt or Ahmed glaucoma valve implantation with pars plana tube insertion in Japanese eyes with neovascular glaucoma: 1-year outcomes
por: Suda, Masayo, et al.
Publicado: (2018)

EYS is a major gene involved in retinitis pigmentosa in Japan: genetic landscapes revealed by stepwise genetic screening
por: Numa, Shogo, et al.
Publicado: (2020)

Real-Time Imaging of Rabbit Retina with Retinal Degeneration by Using Spectral-Domain Optical Coherence Tomography
por: Muraoka, Yuki, et al.
Publicado: (2012)

Changes in the deep vasculature assessed using anterior segment OCT angiography following trabecular meshwork targeted minimally invasive glaucoma surgery
por: Okamoto, Yoko, et al.
Publicado: (2022)

Midget retinal ganglion cell dendritic and mitochondrial degeneration is an early feature of human glaucoma
por: Tribble, James R, et al.
Publicado: (2019)

Longitudinal changes in complete avascular area assessed using anterior segmental optical coherence tomography angiography in filtering trabeculectomy bleb
por: Kido, Ai, et al.
Publicado: (2021)

Nationwide incidence of central retinal artery occlusion in Japan: an exploratory descriptive study using the National Database of Health Insurance Claims (2011–2015)
por: Kido, Ai, et al.
Publicado: (2020)

Prediction of trabecular meshwork-targeted micro-invasive glaucoma surgery outcomes using anterior segment OCT angiography
por: Okamoto, Yoko, et al.
Publicado: (2021)

Retinal Ganglion Cell Degeneration in a Rat Magnetic Bead Model of Ocular Hypertensive Glaucoma
por: Tribble, James R., et al.
Publicado: (2021)

Molecular mechanisms of retinal ganglion cell degeneration in glaucoma and future prospects for cell body and axonal protection
por: Munemasa, Yasunari, et al.
Publicado: (2013)

Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes
por: Hata, Masayuki, et al.
Publicado: (2018)

Use of the structure-function relationship in detecting glaucoma progression in early glaucoma
por: Hirooka, Kazuyuki, et al.
Publicado: (2014)

Adenosine triphosphate maintenance by branched chain amino acids as a novel neuroprotective strategy for retinal neurodegenerative diseases
por: Hasegawa, Tomoko, et al.
Publicado: (2019)

VCP Is an Integral Component of a Novel Feedback Mechanism that Controls Intracellular Localization of Catalase and H(2)O(2) Levels
por: Murakami, Katsuhiro, et al.
Publicado: (2013)

Intrinsically photosensitive retinal ganglion cells in glaucoma
por: Gao, Jingyi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e90ri6l0b7jptpastd3cos9l48