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Acetylcholinesterase and butyrylcholinesterase inhibitory activities of khellactone coumarin derivatives isolated from Peucedanum japonicum Thurnberg

Cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors have been attracted as candidate treatments for Alzheimer's disease (AD). Fifteen khellactone-type coumarins from the roots of Peucedanum japonicum Thunberg were tested for acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and...

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Detalles Bibliográficos
Autores principales: Heo, Jeong Hyun, Eom, Bo Hyun, Ryu, Hyung Won, Kang, Myung-Gyun, Park, Jong Eun, Kim, Doo-Young, Kim, Jung-Hee, Park, Daeui, Oh, Sei-Ryang, Kim, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730441/
https://www.ncbi.nlm.nih.gov/pubmed/33303801
http://dx.doi.org/10.1038/s41598-020-78782-5