Cargando…

NAA10 p.(D10G) and NAA10 p.(L11R) Variants Hamper Formation of the NatA N-Terminal Acetyltransferase Complex

The majority of the human proteome is subjected to N-terminal (Nt) acetylation catalysed by N-terminal acetyltransferases (NATs). The NatA complex is composed of two core subunits—the catalytic subunit NAA10 and the ribosomal anchor NAA15. Furthermore, NAA10 may also have catalytic and non-catalytic...

Descripción completa

Detalles Bibliográficos
Autores principales:	McTiernan, Nina, Darbakk, Christine, Ree, Rasmus, Arnesen, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730585/ https://www.ncbi.nlm.nih.gov/pubmed/33255974 http://dx.doi.org/10.3390/ijms21238973

Ejemplares similares

NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy
por: McTiernan, Nina, et al.
Publicado: (2020)

Hydroxylation of the Acetyltransferase NAA10 Trp38 Is Not an Enzyme-Switch in Human Cells
por: Ree, Rasmus, et al.
Publicado: (2021)

A novel human NatA N(α)-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)
por: Arnesen, Thomas, et al.
Publicado: (2009)

NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant – a case report
por: McTiernan, Nina, et al.
Publicado: (2018)

Severe syndromic ID and skewed X-inactivation in a girl with NAA10 dysfunction and a novel heterozygous de novo NAA10 p.(His16Pro) variant - a case report
por: Bader, Ingrid, et al.
Publicado: (2020)

The N-terminal acetyltransferase Naa10 is essential for zebrafish development
por: Ree, Rasmus, et al.
Publicado: (2015)

Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway
por: Kweon, Hyae Yon, et al.
Publicado: (2021)

N-α-acetyltransferase 10 (NAA10) in development: the role of NAA10
por: Lee, Mi-Ni, et al.
Publicado: (2018)

Naa10 in development and disease
por: Myklebust, Line M., et al.
Publicado: (2015)

The protein N(α)-terminal acetyltransferase hNaa10p (hArd1) is phosphorylated in HEK293 cells
por: Målen, Hiwa, et al.
Publicado: (2009)

A novel NAA10 p.(R83H) variant with impaired acetyltransferase activity identified in two boys with ID and microcephaly
por: Ree, Rasmus, et al.
Publicado: (2019)

Biochemical analysis of novel NAA10 variants suggests distinct pathogenic mechanisms involving impaired protein N-terminal acetylation
por: McTiernan, Nina, et al.
Publicado: (2022)

NAA10-related syndrome
por: Wu, Yiyang, et al.
Publicado: (2018)

Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
por: Myklebust, Line M., et al.
Publicado: (2023)

Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity
por: Weidenhausen, Jonas, et al.
Publicado: (2022)

Characterization of Lysine Acetyltransferase Activity of Recombinant Human ARD1/NAA10
por: Vo, Tam Thuy Lu, et al.
Publicado: (2020)

NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment
por: Casey, Jillian P., et al.
Publicado: (2015)

NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility
por: Drazic, Adrian, et al.
Publicado: (2018)

Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80
por: Goris, Marianne, et al.
Publicado: (2018)

Characterization of Evolutionarily Conserved Trypanosoma cruzi NatC and NatA-N-Terminal Acetyltransferase Complexes
por: Ochaya, Stephen, et al.
Publicado: (2019)

Expanding the Phenotype Associated with NAA10‐Related N‐Terminal Acetylation Deficiency
por: Saunier, Chloé, et al.
Publicado: (2016)

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective
por: Jonckheere, Veronique, et al.
Publicado: (2021)

Ocular Manifestations of the NAA10-Related Syndrome
por: Gupta, Angela S., et al.
Publicado: (2019)

The Human N-Alpha-Acetyltransferase 40 (hNaa40p/hNatD) Is Conserved from Yeast and N-Terminally Acetylates Histones H2A and H4
por: Hole, Kristine, et al.
Publicado: (2011)

Missense NAA20 variants impairing the NatB protein N-terminal acetyltransferase cause autosomal recessive developmental delay, intellectual disability, and microcephaly
por: Morrison, Jennifer, et al.
Publicado: (2021)

Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome
por: Lyon, Gholson J., et al.
Publicado: (2023)

Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase
por: Chen, Ji-Yun, et al.
Publicado: (2016)

ARD1/NAA10 acetylation in prostate cancer
por: Kuhns, Katherine J., et al.
Publicado: (2018)

Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization
por: Starheim, Kristian K., et al.
Publicado: (2017)

Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10)
por: Xu, Huiyu, et al.
Publicado: (2016)

Naa10p Enhances Chemosensitivity to Cisplatin in Oral Squamous Cell Carcinoma Cells
por: Sun, Lichun, et al.
Publicado: (2021)

NAA10 as a New Prognostic Marker for Cancer Progression
por: Kim, Sun Myung, et al.
Publicado: (2020)

Holding it together: Naa60 at the Golgi
por: Aksnes, Henriette, et al.
Publicado: (2015)

Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance
por: Demetriadou, Christina, et al.
Publicado: (2021)

ARD1/NAA10 in hepatocellular carcinoma: pathways and clinical implications
por: Lee, Danbi, et al.
Publicado: (2018)

Versatility of ARD1/NAA10-mediated protein lysine acetylation
por: Vo, Tam Thuy Lu, et al.
Publicado: (2018)

A Japanese boy with NAA10-related syndrome and hypertrophic cardiomyopathy
por: Shishido, Ayumi, et al.
Publicado: (2020)

PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin
por: Ree, Rasmus, et al.
Publicado: (2021)

Molecular Basis for Amino-Terminal Acetylation by the Heterodimeric NatA Complex
por: Liszczak, Glen, et al.
Publicado: (2013)

Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
por: Deng, Sunbin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q8enukqmh4m3ee74uci7sbi911