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Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma

Activities of daily living (ADL) are frequently impaired in patients with hepatocellular carcinoma (HCC). In this retrospective study, we aimed to investigate the effects of physical therapy on ADLs in patients with HCC during hospitalization for cancer treatment. Nineteen patients with HCC were enr...

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Autores principales: Narao, Hayato, Hirota, Keisuke, Koya, Shunji, Tomita, Manabu, Manako, Yuta, Ogawa, Satosi, Nakao, Naomi, Tsutsumi, Tsubasa, Nakano, Dan, Hashida, Ryuki, Kawaguchi, Takumi, Matsuse, Hiroo, Nagamatu, Hiroaki, Torimura, Takuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730642/
https://www.ncbi.nlm.nih.gov/pubmed/33291223
http://dx.doi.org/10.3390/ijerph17239098
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author Narao, Hayato
Hirota, Keisuke
Koya, Shunji
Tomita, Manabu
Manako, Yuta
Ogawa, Satosi
Nakao, Naomi
Tsutsumi, Tsubasa
Nakano, Dan
Hashida, Ryuki
Kawaguchi, Takumi
Matsuse, Hiroo
Nagamatu, Hiroaki
Torimura, Takuji
author_facet Narao, Hayato
Hirota, Keisuke
Koya, Shunji
Tomita, Manabu
Manako, Yuta
Ogawa, Satosi
Nakao, Naomi
Tsutsumi, Tsubasa
Nakano, Dan
Hashida, Ryuki
Kawaguchi, Takumi
Matsuse, Hiroo
Nagamatu, Hiroaki
Torimura, Takuji
author_sort Narao, Hayato
collection PubMed
description Activities of daily living (ADL) are frequently impaired in patients with hepatocellular carcinoma (HCC). In this retrospective study, we aimed to investigate the effects of physical therapy on ADLs in patients with HCC during hospitalization for cancer treatment. Nineteen patients with HCC were enrolled. During hospitalization, patients performed a combination of resistance training, stretching, and aerobic exercise (20–60 min/day). ADLs were assessed using the functional independence measure (FIM). Changes in FIM were evaluated by before–after analysis. No significant difference was seen in Child–Pugh class before and after physical therapy. The bilateral knee extension strength and chair stand test were significantly increased after physical therapy compared with before physical therapy (p = 0.001 and p = 0.008, respectively). The total FIM score was significantly increased after physical therapy compared with that before physical therapy (p = 0.0156). Among the 18 indexes of FIM, the stairs index was significantly improved after physical therapy compared with that before physical therapy (5.9 vs. 6.4 points, p = 0.0241). We demonstrated that physical therapy improved muscle strength without worsening liver function. Furthermore, physical therapy improved FIM, especially in the stairs index, in patients with HCC. Thus, physical therapy may be beneficial in patients with HCC during cancer treatment.
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spelling pubmed-77306422020-12-12 Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma Narao, Hayato Hirota, Keisuke Koya, Shunji Tomita, Manabu Manako, Yuta Ogawa, Satosi Nakao, Naomi Tsutsumi, Tsubasa Nakano, Dan Hashida, Ryuki Kawaguchi, Takumi Matsuse, Hiroo Nagamatu, Hiroaki Torimura, Takuji Int J Environ Res Public Health Article Activities of daily living (ADL) are frequently impaired in patients with hepatocellular carcinoma (HCC). In this retrospective study, we aimed to investigate the effects of physical therapy on ADLs in patients with HCC during hospitalization for cancer treatment. Nineteen patients with HCC were enrolled. During hospitalization, patients performed a combination of resistance training, stretching, and aerobic exercise (20–60 min/day). ADLs were assessed using the functional independence measure (FIM). Changes in FIM were evaluated by before–after analysis. No significant difference was seen in Child–Pugh class before and after physical therapy. The bilateral knee extension strength and chair stand test were significantly increased after physical therapy compared with before physical therapy (p = 0.001 and p = 0.008, respectively). The total FIM score was significantly increased after physical therapy compared with that before physical therapy (p = 0.0156). Among the 18 indexes of FIM, the stairs index was significantly improved after physical therapy compared with that before physical therapy (5.9 vs. 6.4 points, p = 0.0241). We demonstrated that physical therapy improved muscle strength without worsening liver function. Furthermore, physical therapy improved FIM, especially in the stairs index, in patients with HCC. Thus, physical therapy may be beneficial in patients with HCC during cancer treatment. MDPI 2020-12-06 2020-12 /pmc/articles/PMC7730642/ /pubmed/33291223 http://dx.doi.org/10.3390/ijerph17239098 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Narao, Hayato
Hirota, Keisuke
Koya, Shunji
Tomita, Manabu
Manako, Yuta
Ogawa, Satosi
Nakao, Naomi
Tsutsumi, Tsubasa
Nakano, Dan
Hashida, Ryuki
Kawaguchi, Takumi
Matsuse, Hiroo
Nagamatu, Hiroaki
Torimura, Takuji
Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title_full Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title_fullStr Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title_full_unstemmed Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title_short Effects of In-Hospital Physical Therapy on Activities of Daily Living in Patients with Hepatocellular Carcinoma
title_sort effects of in-hospital physical therapy on activities of daily living in patients with hepatocellular carcinoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730642/
https://www.ncbi.nlm.nih.gov/pubmed/33291223
http://dx.doi.org/10.3390/ijerph17239098
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