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Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis
(1) Background: The purpose of this meta-analysis was to investigate associations between physical activity (PA) and risks and mortality of liver cancer (LC) to suggest a minimum physical activity threshold to reduce LC risks and morality. (2) Methods: A database search was performed to identify rel...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730643/ https://www.ncbi.nlm.nih.gov/pubmed/33271947 http://dx.doi.org/10.3390/ijerph17238943 |
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author | Lee, Junga |
author_facet | Lee, Junga |
author_sort | Lee, Junga |
collection | PubMed |
description | (1) Background: The purpose of this meta-analysis was to investigate associations between physical activity (PA) and risks and mortality of liver cancer (LC) to suggest a minimum physical activity threshold to reduce LC risks and morality. (2) Methods: A database search was performed to identify relevant studies on the associations between PA and risks and mortality of LC before August 2020. The PA amounts were divided into three groups (high: ≥3 h/week, moderate: 2–3 h/week, and low: <2 h/week). The pooled relative risks of LC were calculated. (3) Results: A total of 10 prospective cohort studies were included. LC risks and mortality were 26% and 25% lower with high amounts of PA and 23% and 19% lower in moderate amounts of PA, respectively, compared to low amounts of PA. At the vigorous intensity PA level, high and moderate amounts of PA reduced the LC risk by 54% and 45%, respectively. (4) Conclusions: PA helps to reduce LC risks and mortality in a dose-dependent manner. At a minimum, two hours/week PA are mandatory to reduce LC mortality. |
format | Online Article Text |
id | pubmed-7730643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77306432020-12-12 Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis Lee, Junga Int J Environ Res Public Health Review (1) Background: The purpose of this meta-analysis was to investigate associations between physical activity (PA) and risks and mortality of liver cancer (LC) to suggest a minimum physical activity threshold to reduce LC risks and morality. (2) Methods: A database search was performed to identify relevant studies on the associations between PA and risks and mortality of LC before August 2020. The PA amounts were divided into three groups (high: ≥3 h/week, moderate: 2–3 h/week, and low: <2 h/week). The pooled relative risks of LC were calculated. (3) Results: A total of 10 prospective cohort studies were included. LC risks and mortality were 26% and 25% lower with high amounts of PA and 23% and 19% lower in moderate amounts of PA, respectively, compared to low amounts of PA. At the vigorous intensity PA level, high and moderate amounts of PA reduced the LC risk by 54% and 45%, respectively. (4) Conclusions: PA helps to reduce LC risks and mortality in a dose-dependent manner. At a minimum, two hours/week PA are mandatory to reduce LC mortality. MDPI 2020-12-01 2020-12 /pmc/articles/PMC7730643/ /pubmed/33271947 http://dx.doi.org/10.3390/ijerph17238943 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lee, Junga Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title | Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title_full | Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title_fullStr | Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title_full_unstemmed | Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title_short | Associations between Physical Activity and Liver Cancer Risks and Mortality: A Systematic Review and Meta-Analysis |
title_sort | associations between physical activity and liver cancer risks and mortality: a systematic review and meta-analysis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730643/ https://www.ncbi.nlm.nih.gov/pubmed/33271947 http://dx.doi.org/10.3390/ijerph17238943 |
work_keys_str_mv | AT leejunga associationsbetweenphysicalactivityandlivercancerrisksandmortalityasystematicreviewandmetaanalysis |