Cyclodextrin-Based Contrast Agents for Medical Imaging

Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides consisting of multiple glucose subunits. CDs are widely used in host–guest chemistry and biochemistry due to their structural advantages, biocompatibility, and ability to form inclusion complexes. Recently, CDs have become of high i...

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Detalles Bibliográficos
Autores principales: Shepelytskyi, Yurii, Newman, Camryn J., Grynko, Vira, Seveney, Lauren E., DeBoef, Brenton, Hane, Francis T., Albert, Mitchell S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730728/
https://www.ncbi.nlm.nih.gov/pubmed/33261035
http://dx.doi.org/10.3390/molecules25235576
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author Shepelytskyi, Yurii
Newman, Camryn J.
Grynko, Vira
Seveney, Lauren E.
DeBoef, Brenton
Hane, Francis T.
Albert, Mitchell S.
author_facet Shepelytskyi, Yurii
Newman, Camryn J.
Grynko, Vira
Seveney, Lauren E.
DeBoef, Brenton
Hane, Francis T.
Albert, Mitchell S.
author_sort Shepelytskyi, Yurii
collection PubMed
description Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides consisting of multiple glucose subunits. CDs are widely used in host–guest chemistry and biochemistry due to their structural advantages, biocompatibility, and ability to form inclusion complexes. Recently, CDs have become of high interest in the field of medical imaging as a potential scaffold for the development of a large variety of the contrast agents suitable for magnetic resonance imaging, ultrasound imaging, photoacoustic imaging, positron emission tomography, single photon emission computed tomography, and computed tomography. The aim of this review is to summarize and highlight the achievements in the field of cyclodextrin-based contrast agents for medical imaging.
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spelling pubmed-77307282020-12-12 Cyclodextrin-Based Contrast Agents for Medical Imaging Shepelytskyi, Yurii Newman, Camryn J. Grynko, Vira Seveney, Lauren E. DeBoef, Brenton Hane, Francis T. Albert, Mitchell S. Molecules Review Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides consisting of multiple glucose subunits. CDs are widely used in host–guest chemistry and biochemistry due to their structural advantages, biocompatibility, and ability to form inclusion complexes. Recently, CDs have become of high interest in the field of medical imaging as a potential scaffold for the development of a large variety of the contrast agents suitable for magnetic resonance imaging, ultrasound imaging, photoacoustic imaging, positron emission tomography, single photon emission computed tomography, and computed tomography. The aim of this review is to summarize and highlight the achievements in the field of cyclodextrin-based contrast agents for medical imaging. MDPI 2020-11-27 /pmc/articles/PMC7730728/ /pubmed/33261035 http://dx.doi.org/10.3390/molecules25235576 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shepelytskyi, Yurii
Newman, Camryn J.
Grynko, Vira
Seveney, Lauren E.
DeBoef, Brenton
Hane, Francis T.
Albert, Mitchell S.
Cyclodextrin-Based Contrast Agents for Medical Imaging
title Cyclodextrin-Based Contrast Agents for Medical Imaging
title_full Cyclodextrin-Based Contrast Agents for Medical Imaging
title_fullStr Cyclodextrin-Based Contrast Agents for Medical Imaging
title_full_unstemmed Cyclodextrin-Based Contrast Agents for Medical Imaging
title_short Cyclodextrin-Based Contrast Agents for Medical Imaging
title_sort cyclodextrin-based contrast agents for medical imaging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730728/
https://www.ncbi.nlm.nih.gov/pubmed/33261035
http://dx.doi.org/10.3390/molecules25235576
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