Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study

The purpose of this study was to confirm the success rate of surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) in patients at a single institution (Association of Oral and Maxillofacial Surgery (AAOMS) stages 1, 2, or 3), and to identify the factors that influence treatment o...

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Autores principales: Choi, Na Rae, Lee, Jung Han, Park, Jin Young, Hwang, Dae Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730744/
https://www.ncbi.nlm.nih.gov/pubmed/33256211
http://dx.doi.org/10.3390/ijerph17238801
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author Choi, Na Rae
Lee, Jung Han
Park, Jin Young
Hwang, Dae Seok
author_facet Choi, Na Rae
Lee, Jung Han
Park, Jin Young
Hwang, Dae Seok
author_sort Choi, Na Rae
collection PubMed
description The purpose of this study was to confirm the success rate of surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) in patients at a single institution (Association of Oral and Maxillofacial Surgery (AAOMS) stages 1, 2, or 3), and to identify the factors that influence treatment outcomes. As a result of analyzing the outcomes of treatment, surgical “success” was achieved in 93.97% (109) of cases, and “failure” was observed at 6.03% (7) cases. Analysis of patient factors that potentially affect treatment outcomes showed that zoledronate dose (p = 0.005) and the IV (intravenous) injection of drugs (p = 0.044) had significant negative impacts.
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spelling pubmed-77307442020-12-12 Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study Choi, Na Rae Lee, Jung Han Park, Jin Young Hwang, Dae Seok Int J Environ Res Public Health Article The purpose of this study was to confirm the success rate of surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) in patients at a single institution (Association of Oral and Maxillofacial Surgery (AAOMS) stages 1, 2, or 3), and to identify the factors that influence treatment outcomes. As a result of analyzing the outcomes of treatment, surgical “success” was achieved in 93.97% (109) of cases, and “failure” was observed at 6.03% (7) cases. Analysis of patient factors that potentially affect treatment outcomes showed that zoledronate dose (p = 0.005) and the IV (intravenous) injection of drugs (p = 0.044) had significant negative impacts. MDPI 2020-11-26 2020-12 /pmc/articles/PMC7730744/ /pubmed/33256211 http://dx.doi.org/10.3390/ijerph17238801 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Na Rae
Lee, Jung Han
Park, Jin Young
Hwang, Dae Seok
Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title_full Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title_fullStr Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title_full_unstemmed Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title_short Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study
title_sort surgical treatment of medication-related osteonecrosis of the jaw: a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730744/
https://www.ncbi.nlm.nih.gov/pubmed/33256211
http://dx.doi.org/10.3390/ijerph17238801
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AT hwangdaeseok surgicaltreatmentofmedicationrelatedosteonecrosisofthejawaretrospectivestudy

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