Cargando…

Advances in Transgenic Mouse Models to Study Infections by Human Pathogenic Viruses

Medical research is changing into direction of precision therapy, thus, sophisticated preclinical models are urgently needed. In human pathogenic virus research, the major technical hurdle is not only to translate discoveries from animals to treatments of humans, but also to overcome the problem of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masemann, Dörthe, Ludwig, Stephan, Boergeling, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730764/ https://www.ncbi.nlm.nih.gov/pubmed/33291453 http://dx.doi.org/10.3390/ijms21239289

Ejemplares similares

Replication-incompetent influenza A viruses armed with IFN-γ effectively mediate immune modulation and tumor destruction in mice harboring lung cancer
por: Meissner, Ramona, et al.
Publicado: (2023)

Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants
por: Ferrando, Verónica A., et al.
Publicado: (2023)

Altered Signal Transduction in the Immune Response to Influenza Virus and S. pneumoniae or S. aureus Co-Infections
por: Wilden, Janine J., et al.
Publicado: (2021)

The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus
por: Nacken, Wolfgang, et al.
Publicado: (2021)

PD-1 IC Inhibition Synergistically Improves Influenza A Virus-Mediated Oncolysis of Metastatic Pulmonary Melanoma
por: Sitnik, Siarhei, et al.
Publicado: (2020)

Metabolic Modifications by Common Respiratory Viruses and Their Potential as New Antiviral Targets
por: Kleinehr, Jens, et al.
Publicado: (2021)

Cellular Protein Phosphatase 2A Regulates Cell Survival Mechanisms in Influenza A Virus Infection
por: Gerlt, Vanessa, et al.
Publicado: (2021)

Impact of Staphylococcus aureus Small Colony Variants on Human Lung Epithelial Cells with Subsequent Influenza Virus Infection
por: Wilden, Janine J., et al.
Publicado: (2020)

Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways
por: Holzberg, Magdalena, et al.
Publicado: (2017)

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages
por: Masemann, Dörthe, et al.
Publicado: (2018)

The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model
por: Schloer, Sebastian, et al.
Publicado: (2019)

β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling
por: Hillesheim, Andrea, et al.
Publicado: (2014)

Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers
por: Masemann, Dörthe, et al.
Publicado: (2021)

Humanized Mouse Models for the Study of Infection and Pathogenesis of Human Viruses
por: Lai, Fritz, et al.
Publicado: (2018)

Transgenic mouse models for ADHD
por: Leo, Damiana, et al.
Publicado: (2013)

Introducing Human APOE into Aβ Transgenic Mouse Models
por: Tai, Leon M., et al.
Publicado: (2011)

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein
por: Boergeling, Yvonne, et al.
Publicado: (2015)

Current Advances in Humanized Mouse Models for Studying NK Cells and HIV Infection
por: Kim, Jocelyn T., et al.
Publicado: (2023)

Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex
por: Abou Nader, Nour, et al.
Publicado: (2022)

A transgenic mouse model for studying HBV infection in neonate
por: Wang, Zhuo, et al.
Publicado: (2011)

Recent Advances in Proteinuric Kidney Disease/Nephrotic Syndrome: Lessons from Knockout/Transgenic Mouse Models
por: Saiki, Ryosuke, et al.
Publicado: (2023)

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
por: Sanchez-Varo, Raquel, et al.
Publicado: (2022)

Humanized Mouse Models of Epstein-Barr Virus Infection and Associated Diseases
por: Fujiwara, Shigeyoshi, et al.
Publicado: (2013)

A transgenic mouse model of human T cell leukemia virus type 1-associated diseases
por: Ohsugi, Takeo
Publicado: (2013)

Carcinogenesis in transgenic mouse models.
por: Lyon, T
Publicado: (1997)

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease
por: Wirths, Oliver, et al.
Publicado: (2010)

Understanding Tendons: Lessons from Transgenic Mouse Models
por: Delgado Caceres, Manuel, et al.
Publicado: (2018)

Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models
por: Wirths, Oliver, et al.
Publicado: (2020)

Generation of new transgenic SMARCA4‐deficient mouse models results in neuromuscular weakness and paralysis of limbs
por: Neyazi, Sina, et al.
Publicado: (2022)

Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation
por: Mandl, Manuela, et al.
Publicado: (2015)

Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s Disease
por: Unger, M. S., et al.
Publicado: (2016)

The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells—Lessons Learned from Different Transgenic Mouse Models
por: Klaus, Tanja, et al.
Publicado: (2023)

The utilization of humanized mouse models for the study of human retroviral infections
por: Van Duyne, Rachel, et al.
Publicado: (2009)

Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model
por: NOGUCHI, AKIRA, et al.
Publicado: (2013)

Transgenic Mouse Models in Cancer Research
por: Lampreht Tratar, Ursa, et al.
Publicado: (2018)

TRANSGENIC MOUSE MODELS OF ALZHEIMER’S DISEASE
por: Henry-Smith, Charnae A, et al.
Publicado: (2019)

Recent advancements in the measurement of pathogenic airborne viruses
por: Bhardwaj, Jyoti, et al.
Publicado: (2021)

β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer
por: Lahlou, Hicham, et al.
Publicado: (2011)

Development of a humanized HLA‐A30 transgenic mouse model
por: Zhu, Meng‐min, et al.
Publicado: (2022)

Gene-Environment Interaction Research and Transgenic Mouse Models of Alzheimer's Disease
por: Chouliaras, L., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tds47amdb4l5843st7ncng82v6