From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological Systems

Biologically active small molecules have a central role in drug development, and as chemical probes and tool compounds to perturb and elucidate biological processes. Small molecules can be rationally designed for a given target, or a library of molecules can be screened against a target or phenotype...

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Detalles Bibliográficos
Autores principales: Pasquer, Quentin T. L., Tsakoumagkos, Ioannis A., Hoogendoorn, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730769/
https://www.ncbi.nlm.nih.gov/pubmed/33287212
http://dx.doi.org/10.3390/molecules25235702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730769/
https://www.ncbi.nlm.nih.gov/pubmed/33287212
http://dx.doi.org/10.3390/molecules25235702

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