PyClone-VI: scalable inference of clonal population structures using whole genome data

BACKGROUND: At diagnosis tumours are typically composed of a mixture of genomically distinct malignant cell populations. Bulk sequencing of tumour samples coupled with computational deconvolution can be used to identify these populations and study cancer evolution. Existing computational methods for...

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Detalles Bibliográficos
Autores principales: Gillis, Sierra, Roth, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730797/
https://www.ncbi.nlm.nih.gov/pubmed/33302872
http://dx.doi.org/10.1186/s12859-020-03919-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730797/
https://www.ncbi.nlm.nih.gov/pubmed/33302872
http://dx.doi.org/10.1186/s12859-020-03919-2

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