Cargando…
PyClone-VI: scalable inference of clonal population structures using whole genome data
BACKGROUND: At diagnosis tumours are typically composed of a mixture of genomically distinct malignant cell populations. Bulk sequencing of tumour samples coupled with computational deconvolution can be used to identify these populations and study cancer evolution. Existing computational methods for...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730797/ https://www.ncbi.nlm.nih.gov/pubmed/33302872 http://dx.doi.org/10.1186/s12859-020-03919-2 |