Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity

Biliverdin reductase A (BVR-A) is an enzyme involved in the regulation of insulin signalling. Knockout (KO) mice for hepatic BVR-A, on a high-fat diet, develop more severe glucose impairment and hepato-steatosis than the wild type, whereas loss of adipocyte BVR-A is associated with increased viscera...

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Detalles Bibliográficos
Autores principales: Ceccarelli, Valentina, Barchetta, Ilaria, Cimini, Flavia Agata, Bertoccini, Laura, Chiappetta, Caterina, Capoccia, Danila, Carletti, Raffaella, Di Cristofano, Claudio, Silecchia, Gianfranco, Fontana, Mario, Leonetti, Frida, Lenzi, Andrea, Baroni, Marco Giorgio, Barone, Eugenio, Cavallo, Maria Gisella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730815/
https://www.ncbi.nlm.nih.gov/pubmed/33260451
http://dx.doi.org/10.3390/ijms21239091

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