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Development of Taccalonolide AJ-Hydroxypropyl-β-Cyclodextrin Inclusion Complexes for Treatment of Clear Cell Renal-Cell Carcinoma

Background: Microtubule-targeted drugs are the most effective drugs for adult patients with certain solid tumors. Taccalonolide AJ (AJ) can stabilize tubulin polymerization by covalently binding to β-tubulin, which enables it to play a role in the treatment of tumors. However, its clinical applicati...

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Detalles Bibliográficos
Autores principales: Han, Jing, Zhang, Siwang, Niu, Junxin, Zhang, Chunli, Dai, Weichen, Wu, Yuanyuan, Hu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731059/
https://www.ncbi.nlm.nih.gov/pubmed/33261151
http://dx.doi.org/10.3390/molecules25235586

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