Structural, Pro-Inflammatory and Calcium Handling Remodeling Underlies Spontaneous Onset of Paroxysmal Atrial Fibrillation in JDP2-Overexpressing Mice

Background: Cardiac-specific JDP2 overexpression provokes ventricular dysfunction and atrial dilatation in mice. We performed in vivo studies on JDP2-overexpressing mice to investigate the impact of JDP2 on the predisposition to spontaneous atrial fibrillation (AF). Methods: JDP2-overexpression was...

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Detalles Bibliográficos
Autores principales: Parahuleva, Mariana S., Kockskämper, Jens, Heger, Jacqueline, Grimm, Wolfram, Scherer, Anna, Bühler, Sarah, Kreutz, Julian, Schulz, Rainer, Euler, Gerhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731172/
https://www.ncbi.nlm.nih.gov/pubmed/33265909
http://dx.doi.org/10.3390/ijms21239095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731172/
https://www.ncbi.nlm.nih.gov/pubmed/33265909
http://dx.doi.org/10.3390/ijms21239095

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