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Intermolecular Interactions in Crystal Structures of Imatinib-Containing Compounds

Imatinib, one of the most used therapeutic agents to treat leukemia, is an inhibitor that specifically blocks the activity of tyrosine kinases. The molecule of imatinib is flexible and contains several functional groups able to take part in H-bonding and hydrophobic interactions. Analysis of molecul...

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Detalles Bibliográficos
Autores principales: Vologzhanina, Anna V., Ushakov, Ivan E., Korlyukov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731260/
https://www.ncbi.nlm.nih.gov/pubmed/33255944
http://dx.doi.org/10.3390/ijms21238970