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Post-translational modifications of EZH2 in cancer

Enhancer of zeste homolog 2 (EZH2), as a main component of Polycomb Repressive Complex 2, catalyzes histone H3K27me3 to silence its target gene expression. EZH2 upregulation results in cancer development and poor prognosis of cancer patients. Post-translational modifications (PTMs) are important bio...

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Detalles Bibliográficos
Autores principales:	Li, Zhongwei, Li, Minle, Wang, Diandian, Hou, Pingfu, Chen, Xintian, Chu, Sufang, Chai, Dafei, Zheng, Junnian, Bai, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731458/ https://www.ncbi.nlm.nih.gov/pubmed/33308321 http://dx.doi.org/10.1186/s13578-020-00505-0

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