Cargando…

Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), as well as SARS-CoV from 2003 along with MERS-CoV from 2012, is a member of the Betacoronavirus genus of the Nidovirales order and is currently the cause of the pandemic called COVID-19 (or Coronavirus disease 2019). COVID-19, which is ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simabuco, Fernando Moreira, Tamura, Rodrigo Esaki, Pavan, Isadora Carolina Betim, Morale, Mirian Galliote, Ventura, Armando Morais
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731901/ https://www.ncbi.nlm.nih.gov/pubmed/33237152 http://dx.doi.org/10.1590/1678-4685-GMB-2020-0212

Ejemplares similares

Metformin and Cancer Hallmarks: Molecular Mechanisms in Thyroid, Prostate and Head and Neck Cancer Models
por: Morale, Mirian Galliote, et al.
Publicado: (2022)

TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line
por: Morale, Mirian Galliote, et al.
Publicado: (2022)

p53 and metabolism: from mechanism to therapeutics
por: Simabuco, Fernando M., et al.
Publicado: (2018)

Correction: p53 and metabolism: from mechanism to therapeutics
por: Simabuco, Fernando M., et al.
Publicado: (2018)

The use of adenoviral vectors in gene therapy and vaccine approaches
por: Araújo, Natália Meneses, et al.
Publicado: (2022)

Checking NEKs: Overcoming a Bottleneck in Human Diseases
por: Peres de Oliveira, Andressa, et al.
Publicado: (2020)

The Hallmarks of Flavonoids in Cancer
por: Ponte, Luis Gustavo Saboia, et al.
Publicado: (2021)

HPV-transformed cells exhibit altered HMGB1-TLR4/MyD88-SARM1 signaling axis
por: Morale, Mirian Galliote, et al.
Publicado: (2018)

Innate immunity and HPV: friends or foes
por: Nunes, Rafaella Almeida Lima, et al.
Publicado: (2018)

The respiratory syncytial virus M2-2 protein is targeted for proteasome degradation and inhibits translation and stress granules assembly
por: Scudero, Orlando Bonito, et al.
Publicado: (2023)

Oxidative stress: therapeutic approaches for cervical cancer treatment
por: Silva, Gabriela Ávila Fernandes, et al.
Publicado: (2018)

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration
por: Tamura, Rodrigo E., et al.
Publicado: (2016)

Gene optimization leads to robust expression of human respiratory syncytial virus nucleoprotein and phosphoprotein in human cells and induction of humoral immunity in mice
por: Simabuco, Fernando M., et al.
Publicado: (2009)

S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells
por: Amaral, Camila L., et al.
Publicado: (2016)

NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells
por: Pavan, Isadora Carolina Betim, et al.
Publicado: (2023)

Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target
por: Zambalde, Érika Pereira, et al.
Publicado: (2022)

On Broken Ne(c)ks and Broken DNA: The Role of Human NEKs in the DNA Damage Response
por: Pavan, Isadora Carolina Betim, et al.
Publicado: (2021)

Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways
por: Morelli, Ana Paula, et al.
Publicado: (2021)

Characterization of the different S6Ks isoforms interacting partners
por: Pavan, Isadora, et al.
Publicado: (2014)

HPV-Mediated Resistance to TNF and TRAIL Is Characterized by Global Alterations in Apoptosis Regulatory Factors, Dysregulation of Death Receptors, and Induction of ROS/RNS
por: Cabeça, Tatiane Karen, et al.
Publicado: (2019)

Replication Cycle of Astroviruses
por: Méndez, Ernesto, et al.
Publicado: (2012)

STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma
por: Morelli, Ana Paula, et al.
Publicado: (2021)

Characterization of pomegranate peel extracts obtained using different solvents and their effects on cell cycle and apoptosis in leukemia cells
por: Tamborlin, Leticia, et al.
Publicado: (2020)

In-depth analysis of the replication cycle of Orpheovirus
por: Souza, Fernanda, et al.
Publicado: (2019)

Biochemical Aspects of Coronavirus Replication
por: Enjuanes, Luis, et al.
Publicado: (2006)

Structural Analysis of Human Respiratory Syncytial Virus P Protein: Identification of Intrinsically Disordered Domains
por: Simabuco, Fernando M., et al.
Publicado: (2011)

Forthcoming Developments in Models to Study the Hepatitis B Virus Replication Cycle, Pathogenesis, and Pharmacological Advancements
por: Bhat, Sajad Ahmad, et al.
Publicado: (2023)

Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle
por: Keyaerts, Els, et al.
Publicado: (2007)

Coronavirus replication factories
por: Du Toit, Andrea
Publicado: (2020)

Coronavirus Genome Replication
por: Sawicki, Stanley G.
Publicado: (2008)

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine
por: de Oliveira, Liliane Maria Fernandes, et al.
Publicado: (2015)

Cedratvirus getuliensis replication cycle: an in-depth morphological analysis
por: Silva, Ludmila Karen dos Santos, et al.
Publicado: (2018)

Involvement of Autophagy in Coronavirus Replication
por: Maier, Helena J., et al.
Publicado: (2012)

Coronaviruses: An Overview of Their Replication and Pathogenesis
por: Fehr, Anthony R., et al.
Publicado: (2015)

Host Factors in Coronavirus Replication
por: de Wilde, Adriaan H., et al.
Publicado: (2017)

Coronavirus Genome Structure and Replication
por: Brian, D. A., et al.
Publicado: (2005)

Unbalanced Growth, the DNA Replication Cycle and Discovery of Repair Replication
por: Hanawalt, Philip C.
Publicado: (2023)

ADAM17 mediates OSCC development in an orthotopic murine model
por: Simabuco, Fernando Moreira, et al.
Publicado: (2014)

RNA-RNA and RNA-protein interactions in coronavirus replication and transcription
por: Sola, Isabel, et al.
Publicado: (2011)

Early steps of retrovirus replicative cycle
por: Nisole, Sébastien, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_um88opdkqu3gcobfdbqh5sfg8c