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Region-specific and dose-specific effects of chronic haloperidol exposure on [(3)H]-flumazenil and [(3)H]-Ro15-4513 GABA(A) receptor binding sites in the rat brain

Postmortem studies suggest that schizophrenia is associated with abnormal expression of specific GABA(A) receptor (GABA(A)R) α subunits, including α5GABA(A)R. Positron emission tomography (PET) measures of GABA(A)R availability in schizophrenia, however, have not revealed consistent alterations in v...

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Detalles Bibliográficos
Autores principales: Peris-Yague, Alba, Kiemes, Amanda, Cash, Diana, Cotel, Marie-Caroline, Singh, Nisha, Vernon, Anthony C., Modinos, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731940/
https://www.ncbi.nlm.nih.gov/pubmed/33153853
http://dx.doi.org/10.1016/j.euroneuro.2020.10.004