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Computational insights into fluconazole resistance by the suspected mutations in lanosterol 14α-demethylase (Erg11p) of Candida albicans
Mutations in the ergosterol biosynthesis gene 11 (ERG11) of Candida albicans have been frequently reported in fluconazole-resistant clinical isolates. Exploring the mutations and their effect could provide new insights into the underlying mechanism of fluconazole resistance. Erg11p_Threonine285Alani...
Autores principales: | Prakash, Sagunthala Murugesan Udaya, Nazeer, Yasin, Jayanthi, Sivaraman, Kabir, Mohammad Anaul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731972/ https://www.ncbi.nlm.nih.gov/pubmed/33344662 http://dx.doi.org/10.22099/mbrc.2020.36298.1476 |
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