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Quality of CD8(+) T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context
Revealing the mechanisms that underlie the expansion of antitumor CD8(+) T cells that are associated with improved clinical outcomes is critical to improving immunotherapeutic management of melanoma. How the lymphatic system, which orchestrates the complex sensing of antigen by lymphocytes to mount...
Autores principales: | O’Melia, M. J., Rohner, N. A., Manspeaker, M. P., Francis, D. M., Kissick, H. T., Thomas, S. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732197/ https://www.ncbi.nlm.nih.gov/pubmed/33310857 http://dx.doi.org/10.1126/sciadv.abd7134 |
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