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Integrative genomics analysis identifies promising SNPs and genes implicated in tuberculosis risk based on multiple omics datasets

More than 10 GWASs have reported numerous genetic loci associated with tuberculosis (TB). However, the functional effects of genetic variants on TB remains largely unknown. In the present study, by combining a reported GWAS summary dataset (N = 452,264) with 3 independent eQTL datasets (N = 2,242) a...

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Detalles Bibliográficos
Autores principales: Xu, Mengqiu, Li, Jingjing, Xiao, Zhaoying, Lou, Jiongpo, Pan, Xinrong, Ma, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732298/
https://www.ncbi.nlm.nih.gov/pubmed/33051402
http://dx.doi.org/10.18632/aging.103744