Cargando…

Integrative genomics analysis identifies promising SNPs and genes implicated in tuberculosis risk based on multiple omics datasets

More than 10 GWASs have reported numerous genetic loci associated with tuberculosis (TB). However, the functional effects of genetic variants on TB remains largely unknown. In the present study, by combining a reported GWAS summary dataset (N = 452,264) with 3 independent eQTL datasets (N = 2,242) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Mengqiu, Li, Jingjing, Xiao, Zhaoying, Lou, Jiongpo, Pan, Xinrong, Ma, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732298/ https://www.ncbi.nlm.nih.gov/pubmed/33051402 http://dx.doi.org/10.18632/aging.103744

Ejemplares similares

Integrative genomics analysis identifies five promising genes implicated in insomnia risk based on multiple omics datasets
por: Sun, Haozhen, et al.
Publicado: (2020)

Integrated genomics analysis highlights important SNPs and genes implicated in moderate-to-severe asthma based on GWAS and eQTL datasets
por: Dong, Zhouzhou, et al.
Publicado: (2020)

Integrating omics datasets with the OmicsPLS package
por: Bouhaddani, Said el, et al.
Publicado: (2018)

Multiple kernel learning for integrative consensus clustering of omic datasets
por: Cabassi, Alessandra, et al.
Publicado: (2020)

integrOmics: an R package to unravel relationships between two omics datasets
por: Lê Cao, Kim-Anh, et al.
Publicado: (2009)

A multivariate approach to the integration of multi-omics datasets
por: Meng, Chen, et al.
Publicado: (2014)

An integrative imputation method based on multi-omics datasets
por: Lin, Dongdong, et al.
Publicado: (2016)

A Review of Integrative Imputation for Multi-Omics Datasets
por: Song, Meng, et al.
Publicado: (2020)

PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases
por: Liu, Tianyuan, et al.
Publicado: (2022)

Integrative analysis of multiple diverse omics datasets by sparse group multitask regression
por: Lin, Dongdong, et al.
Publicado: (2014)

Improvement of prediction ability by integrating multi-omic datasets in barley
por: Wu, Po-Ya, et al.
Publicado: (2022)

OmicsARules: a R package for integration of multi-omics datasets via association rules mining
por: Chen, Danze, et al.
Publicado: (2019)

Statistical integration of two omics datasets using GO2PLS
por: Gu, Zhujie, et al.
Publicado: (2021)

Integrative Omics for Identifying Dysfunctional Pathways in CKD
por: Tin, Adrienne, et al.
Publicado: (2018)

Integrating multiple ‘omics’ analyses identifies serological protein biomarkers for preeclampsia
por: Liu, Linda Y, et al.
Publicado: (2013)

Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits
por: Gleason, Kevin J., et al.
Publicado: (2020)

OmicLoupe: facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons
por: Willforss, Jakob, et al.
Publicado: (2021)

Integrating nutriepigenomics in Parkinson’s disease management: New promising strategy in the omics era
por: Razali, Khairiah, et al.
Publicado: (2022)

Integrative genomics analysis of various omics data and networks identify risk genes and variants vulnerable to childhood-onset asthma
por: Ma, Xiuqing, et al.
Publicado: (2020)

Model-based joint visualization of multiple compositional omics datasets
por: Hawinkel, Stijn, et al.
Publicado: (2020)

Integrating AI/ML Models for Patient Stratification Leveraging Omics Dataset and Clinical Biomarkers from COVID-19 Patients: A Promising Approach to Personalized Medicine
por: Bello, Babatunde, et al.
Publicado: (2023)

A data-fusion approach to identifying developmental dyslexia from multi-omics datasets
por: Carrion, Jackson, et al.
Publicado: (2023)

Exploring the novel SNPs in neuroticism and birth weight based on GWAS datasets
por: Zhou, Xiao-Ying, et al.
Publicado: (2023)

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
por: Kapoor, Manav, et al.
Publicado: (2021)

omicplotR: visualizing omic datasets as compositions
por: Giguere, Daniel J., et al.
Publicado: (2019)

Promise of spatially resolved omics for tumor research
por: Zhou, Yanhe, et al.
Publicado: (2023)

Association Between SNPs in the One-Carbon Metabolism Pathway and the Risk of Female Breast Cancer in a Chinese Population
por: Wang, Xuhong, et al.
Publicado: (2022)

Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV
por: Krishnan, Sonya, et al.
Publicado: (2021)

Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package
por: Tuncbag, Nurcan, et al.
Publicado: (2016)

Genomic Identification of RNA Editing Through Integrating Omics Datasets and the Clinical Relevance in Hepatocellular Carcinoma
por: Chen, Juan, et al.
Publicado: (2020)

DRPPM-EASY: A Web-Based Framework for Integrative Analysis of Multi-Omics Cancer Datasets
por: Obermayer, Alyssa, et al.
Publicado: (2022)

Integration of a multi-omics stem cell differentiation dataset using a dynamical model
por: van den Berg, Patrick R., et al.
Publicado: (2023)

Comprehensive Survey of SNPs in the Affymetrix Exon Array Using the 1000 Genomes Dataset
por: Gamazon, Eric R., et al.
Publicado: (2010)

Annotation of susceptibility SNPs associated with atrial fibrillation
por: Xu, Chengqi, et al.
Publicado: (2020)

SGI: automatic clinical subgroup identification in omics datasets
por: Buyukozkan, Mustafa, et al.
Publicado: (2021)

mixOmics: An R package for ‘omics feature selection and multiple data integration
por: Rohart, Florian, et al.
Publicado: (2017)

Diagnostic ‘omics’ for active tuberculosis
por: Haas, Carolin T., et al.
Publicado: (2016)

The Promises, Challenges, and Opportunities of Omics for Studying the Plant Holobiont
por: Carper, Dana L., et al.
Publicado: (2022)

UINMF performs mosaic integration of single-cell multi-omic datasets using nonnegative matrix factorization
por: Kriebel, April R., et al.
Publicado: (2022)

A multi-omics dataset of human transcriptome and proteome stable reference
por: Lu, Shaohua, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5s4uv9inp0avb7nspuccjko0sn