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Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice
The liver gradually loses its regenerative capabilities with aging. However, it remains unknown whether aging affects drug-induced liver injury. Here, we used acetaminophen induced acute liver injury model to compare tissue injury and regeneration of aged mice (>80 weeks old) with young ones (8–1...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732315/ https://www.ncbi.nlm.nih.gov/pubmed/33001859 http://dx.doi.org/10.18632/aging.103973 |