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Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice

The liver gradually loses its regenerative capabilities with aging. However, it remains unknown whether aging affects drug-induced liver injury. Here, we used acetaminophen induced acute liver injury model to compare tissue injury and regeneration of aged mice (>80 weeks old) with young ones (8–1...

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Detalles Bibliográficos
Autores principales:	Tanimizu, Naoki, Ichinohe, Norihisa, Suzuki, Hiromu, Mitaka, Toshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732315/ https://www.ncbi.nlm.nih.gov/pubmed/33001859 http://dx.doi.org/10.18632/aging.103973

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