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Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization

NLRP3 inflammasome activation and complement-mediated inflammation have been implicated in promoting choroidal neovascularization (CNV) in age-related macular degeneration (AMD), but central questions regarding their contributions to AMD pathogenesis remain unanswered. Key open questions are (1) whe...

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Detalles Bibliográficos
Autores principales:	Malsy, Jakob, Alvarado, Andrea C, Lamontagne, Joseph O, Strittmatter, Karin, Marneros, Alexander G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732340/ https://www.ncbi.nlm.nih.gov/pubmed/33305736 http://dx.doi.org/10.7554/eLife.60194

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