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ABCG1 Attenuates Oxidative Stress Induced by H(2)O(2) through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells

Summary. Oxidative stress is an important factor that is related to endothelial dysfunction. ATP-binding cassette transporter G1 (ABCG1), a regulator of intracellular cholesterol efflux, has been found to prevent endothelial activation in vessel walls. To explore the role of ABCG1 in oxidative stres...

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Detalles Bibliográficos
Autores principales: Xue, Jiahong, Fan, Jiali, Li, Yuan, Wu, Wenhuan, Yan, Qing, Zheng, Qiangsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732382/
https://www.ncbi.nlm.nih.gov/pubmed/33344146
http://dx.doi.org/10.1155/2020/2095645