The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission

BACKGROUND: The calcium-sensing receptor (CaSR) plays a fundamental role in extracellular calcium homeostasis in humans. Surprisingly, CaSR is also expressed in nonhomeostatic tissues and is involved in regulating diverse cellular functions. The objective of this study was to determine if Calhex-231...

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Detalles Bibliográficos
Autores principales: Lei, Yan, Peng, Xiaoyong, Hu, Yi, Xue, Mingying, Li, Tao, Liu, Liangming, Yang, Guangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732383/
https://www.ncbi.nlm.nih.gov/pubmed/33343806
http://dx.doi.org/10.1155/2020/4132785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732383/
https://www.ncbi.nlm.nih.gov/pubmed/33343806
http://dx.doi.org/10.1155/2020/4132785

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