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The Calcilytic Drug Calhex-231 Ameliorates Vascular Hyporesponsiveness in Traumatic Hemorrhagic Shock by Inhibiting Oxidative Stress and miR-208a-Mediated Mitochondrial Fission
BACKGROUND: The calcium-sensing receptor (CaSR) plays a fundamental role in extracellular calcium homeostasis in humans. Surprisingly, CaSR is also expressed in nonhomeostatic tissues and is involved in regulating diverse cellular functions. The objective of this study was to determine if Calhex-231...
Autores principales: | Lei, Yan, Peng, Xiaoyong, Hu, Yi, Xue, Mingying, Li, Tao, Liu, Liangming, Yang, Guangming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732383/ https://www.ncbi.nlm.nih.gov/pubmed/33343806 http://dx.doi.org/10.1155/2020/4132785 |
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