Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Rheumatoid arthritis (RA) is a complex autoimmune disease targeting synovial joints. Traditionally, RA is divided into seropositive (SP) and seronegative (SN) disease forms, the latter consisting of an array of unrelated diseases with joint involvement. Recently, we described a severe form of SN-RA...

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Detalles Bibliográficos
Autores principales: Kelkka, Tiina, Savola, Paula, Bhattacharya, Dipabarna, Huuhtanen, Jani, Lönnberg, Tapio, Kankainen, Matti, Paalanen, Kirsi, Tyster, Mikko, Lepistö, Maija, Ellonen, Pekka, Smolander, Johannes, Eldfors, Samuli, Yadav, Bhagwan, Khan, Sofia, Koivuniemi, Riitta, Sjöwall, Christopher, Elo, Laura L., Lähdesmäki, Harri, Maeda, Yuka, Nishikawa, Hiroyoshi, Leirisalo-Repo, Marjatta, Sokka-Isler, Tuulikki, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732449/
https://www.ncbi.nlm.nih.gov/pubmed/33329548
http://dx.doi.org/10.3389/fimmu.2020.578848

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