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Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, has emerged as a global pandemic worldwide. In this study, we used ARTIC primers–based amplicon sequencing to profile 225 SARS-CoV-2 genomes from India. Phylogenetic analysis of 202...

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Detalles Bibliográficos
Autores principales: Raghav, Sunil, Ghosh, Arup, Turuk, Jyotirmayee, Kumar, Sugandh, Jha, Atimukta, Madhulika, Swati, Priyadarshini, Manasi, Biswas, Viplov K., Shyamli, P. Sushree, Singh, Bharati, Singh, Neha, Singh, Deepika, Datey, Ankita, Avula, Kiran, Smita, Shuchi, Sabat, Jyotsnamayee, Bhattacharya, Debdutta, Kshatri, Jaya Singh, Vasudevan, Dileep, Suryawanshi, Amol, Dash, Rupesh, Senapati, Shantibhushan, Beuria, Tushar K., Swain, Rajeeb, Chattopadhyay, Soma, Syed, Gulam Hussain, Dixit, Anshuman, Prasad, Punit, Pati, Sanghamitra, Parida, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732478/
https://www.ncbi.nlm.nih.gov/pubmed/33329480
http://dx.doi.org/10.3389/fmicb.2020.594928