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NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter

Obesity has become a serious problem in public health worldwide, causing numerous metabolic diseases. Once the differentiation to mature adipocytes is disrupted, adipocyte hypertrophy and ectopic lipid accumulation leads to the inflammation in adipose tissue and systemic metabolic disorders. Intrace...

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Detalles Bibliográficos
Autores principales:	Okabe, Keisuke, Nawaz, Allah, Nishida, Yasuhiro, Yaku, Keisuke, Usui, Isao, Tobe, Kazuyuki, Nakagawa, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732485/ https://www.ncbi.nlm.nih.gov/pubmed/33330464 http://dx.doi.org/10.3389/fcell.2020.586179

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