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Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives
PURPOSE OF REVIEW: Environmental pollutants are threat to human beings. Pollutants can lead to human health and environment hazards. The purpose of this review is to summarize the work done on detection of environmental pollutants using DNA nanosensors and challenges in the areas that can be focused...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732738/ https://www.ncbi.nlm.nih.gov/pubmed/33344145 http://dx.doi.org/10.1007/s40726-020-00165-1 |
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author | Kumar, Vineet Guleria, Praveen |
author_facet | Kumar, Vineet Guleria, Praveen |
author_sort | Kumar, Vineet |
collection | PubMed |
description | PURPOSE OF REVIEW: Environmental pollutants are threat to human beings. Pollutants can lead to human health and environment hazards. The purpose of this review is to summarize the work done on detection of environmental pollutants using DNA nanosensors and challenges in the areas that can be focused for safe environment. RECENT FINDINGS: Most of the DNA-based nanosensors designed so far use DNA as recognition element. ssDNA, dsDNA, complementary mismatched DNA, aptamers, and G-quadruplex DNA are commonly used as probes in nanosensors. More and more DNA sequences are being designed that can specifically detect various pollutants even simultaneously in complex milk, wastewater, soil, blood, tap water, river, and pond water samples. The feasibility of direct detection, ease of designing, and analysis makes DNA nanosensors fit for future point-of-care applications. SUMMARY: DNA nanosensors are easy to design and have good sensitivity. DNA component and nanomaterials can be designed in a controlled manner to detect various environmental pollutants. This review identifies the recent advances in DNA nanosensor designing and opportunities available to design nanosensors for unexplored pathogens, antibiotics, pesticides, GMO, heavy metals, and other toxic pollutant. |
format | Online Article Text |
id | pubmed-7732738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-77327382020-12-14 Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives Kumar, Vineet Guleria, Praveen Curr Pollut Rep Biology and Pollution (G O’Mullan and R Boopathy, Section Editors) PURPOSE OF REVIEW: Environmental pollutants are threat to human beings. Pollutants can lead to human health and environment hazards. The purpose of this review is to summarize the work done on detection of environmental pollutants using DNA nanosensors and challenges in the areas that can be focused for safe environment. RECENT FINDINGS: Most of the DNA-based nanosensors designed so far use DNA as recognition element. ssDNA, dsDNA, complementary mismatched DNA, aptamers, and G-quadruplex DNA are commonly used as probes in nanosensors. More and more DNA sequences are being designed that can specifically detect various pollutants even simultaneously in complex milk, wastewater, soil, blood, tap water, river, and pond water samples. The feasibility of direct detection, ease of designing, and analysis makes DNA nanosensors fit for future point-of-care applications. SUMMARY: DNA nanosensors are easy to design and have good sensitivity. DNA component and nanomaterials can be designed in a controlled manner to detect various environmental pollutants. This review identifies the recent advances in DNA nanosensor designing and opportunities available to design nanosensors for unexplored pathogens, antibiotics, pesticides, GMO, heavy metals, and other toxic pollutant. Springer International Publishing 2020-12-12 /pmc/articles/PMC7732738/ /pubmed/33344145 http://dx.doi.org/10.1007/s40726-020-00165-1 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Biology and Pollution (G O’Mullan and R Boopathy, Section Editors) Kumar, Vineet Guleria, Praveen Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title | Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title_full | Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title_fullStr | Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title_full_unstemmed | Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title_short | Application of DNA-Nanosensor for Environmental Monitoring: Recent Advances and Perspectives |
title_sort | application of dna-nanosensor for environmental monitoring: recent advances and perspectives |
topic | Biology and Pollution (G O’Mullan and R Boopathy, Section Editors) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732738/ https://www.ncbi.nlm.nih.gov/pubmed/33344145 http://dx.doi.org/10.1007/s40726-020-00165-1 |
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