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Characterization of Gene Repression by Designed Transcription Activator-like Effector Dimer Proteins
Gene regulation by control of transcription initiation is a fundamental property of living cells. Much of our understanding of gene repression originated from studies of the Escherichia coli lac operon switch, in which DNA looping plays an essential role. To validate and generalize principles from l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732741/ https://www.ncbi.nlm.nih.gov/pubmed/33091377 http://dx.doi.org/10.1016/j.bpj.2020.10.007 |