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Characterization of Gene Repression by Designed Transcription Activator-like Effector Dimer Proteins

Gene regulation by control of transcription initiation is a fundamental property of living cells. Much of our understanding of gene repression originated from studies of the Escherichia coli lac operon switch, in which DNA looping plays an essential role. To validate and generalize principles from l...

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Detalles Bibliográficos
Autores principales: Becker, Nicole A., Peters, Justin P., Schwab, Tanya L., Phillips, William J., Wallace, Jordan P., Clark, Karl J., Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732741/
https://www.ncbi.nlm.nih.gov/pubmed/33091377
http://dx.doi.org/10.1016/j.bpj.2020.10.007