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The human primary somatosensory cortex encodes imagined movement in the absence of sensory information

Classical systems neuroscience positions primary sensory areas as early feed-forward processing stations for refining incoming sensory information. This view may oversimplify their role given extensive bi-directional connectivity with multimodal cortical and subcortical regions. Here we show that si...

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Autores principales: Jafari, Matiar, Aflalo, Tyson, Chivukula, Srinivas, Kellis, Spencer Sterling, Salas, Michelle Armenta, Norman, Sumner Lee, Pejsa, Kelsie, Liu, Charles Yu, Andersen, Richard Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732821/
https://www.ncbi.nlm.nih.gov/pubmed/33311578
http://dx.doi.org/10.1038/s42003-020-01484-1
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author Jafari, Matiar
Aflalo, Tyson
Chivukula, Srinivas
Kellis, Spencer Sterling
Salas, Michelle Armenta
Norman, Sumner Lee
Pejsa, Kelsie
Liu, Charles Yu
Andersen, Richard Alan
author_facet Jafari, Matiar
Aflalo, Tyson
Chivukula, Srinivas
Kellis, Spencer Sterling
Salas, Michelle Armenta
Norman, Sumner Lee
Pejsa, Kelsie
Liu, Charles Yu
Andersen, Richard Alan
author_sort Jafari, Matiar
collection PubMed
description Classical systems neuroscience positions primary sensory areas as early feed-forward processing stations for refining incoming sensory information. This view may oversimplify their role given extensive bi-directional connectivity with multimodal cortical and subcortical regions. Here we show that single units in human primary somatosensory cortex encode imagined reaches in a cognitive motor task, but not other sensory–motor variables such as movement plans or imagined arm position. A population reference-frame analysis demonstrates coding relative to the cued starting hand location suggesting that imagined reaching movements are encoded relative to imagined limb position. These results imply a potential role for primary somatosensory cortex in cognitive imagery, engagement during motor production in the absence of sensation or expected sensation, and suggest that somatosensory cortex can provide control signals for future neural prosthetic systems.
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spelling pubmed-77328212020-12-17 The human primary somatosensory cortex encodes imagined movement in the absence of sensory information Jafari, Matiar Aflalo, Tyson Chivukula, Srinivas Kellis, Spencer Sterling Salas, Michelle Armenta Norman, Sumner Lee Pejsa, Kelsie Liu, Charles Yu Andersen, Richard Alan Commun Biol Article Classical systems neuroscience positions primary sensory areas as early feed-forward processing stations for refining incoming sensory information. This view may oversimplify their role given extensive bi-directional connectivity with multimodal cortical and subcortical regions. Here we show that single units in human primary somatosensory cortex encode imagined reaches in a cognitive motor task, but not other sensory–motor variables such as movement plans or imagined arm position. A population reference-frame analysis demonstrates coding relative to the cued starting hand location suggesting that imagined reaching movements are encoded relative to imagined limb position. These results imply a potential role for primary somatosensory cortex in cognitive imagery, engagement during motor production in the absence of sensation or expected sensation, and suggest that somatosensory cortex can provide control signals for future neural prosthetic systems. Nature Publishing Group UK 2020-12-11 /pmc/articles/PMC7732821/ /pubmed/33311578 http://dx.doi.org/10.1038/s42003-020-01484-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Jafari, Matiar
Aflalo, Tyson
Chivukula, Srinivas
Kellis, Spencer Sterling
Salas, Michelle Armenta
Norman, Sumner Lee
Pejsa, Kelsie
Liu, Charles Yu
Andersen, Richard Alan
The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title_full The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title_fullStr The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title_full_unstemmed The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title_short The human primary somatosensory cortex encodes imagined movement in the absence of sensory information
title_sort human primary somatosensory cortex encodes imagined movement in the absence of sensory information
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732821/
https://www.ncbi.nlm.nih.gov/pubmed/33311578
http://dx.doi.org/10.1038/s42003-020-01484-1
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