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Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds

The thymus is a primary lymphoid organ, essential for T cell maturation and selection. There has been long-standing interest in processes underpinning thymus generation and the potential to manipulate it clinically, because alterations of thymus development or function can result in severe immunodef...

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Detalles Bibliográficos
Autores principales: Campinoti, Sara, Gjinovci, Asllan, Ragazzini, Roberta, Zanieri, Luca, Ariza-McNaughton, Linda, Catucci, Marco, Boeing, Stefan, Park, Jong-Eun, Hutchinson, John C., Muñoz-Ruiz, Miguel, Manti, Pierluigi G., Vozza, Gianluca, Villa, Carlo E., Phylactopoulos, Demetra-Ellie, Maurer, Constance, Testa, Giuseppe, Stauss, Hans J., Teichmann, Sarah A., Sebire, Neil J., Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732825/
https://www.ncbi.nlm.nih.gov/pubmed/33311516
http://dx.doi.org/10.1038/s41467-020-20082-7