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Phospholipase C epsilon mediates cytokine cascade induced by acute disruption of epidermal permeability barrier in mice
Disruption of epidermal barrier is an important trigger in abnormal cutaneous inflammation. Phospholipase C epsilon (PLCε), a Ras/Rap1 effector, is essential for regulating cytokines production in different types of skin inflammation. Our previous studies have demonstrated that elevated expression o...
Autores principales: | Zhang, Jing, Wu, Jiangmei, Sun, Mengke, Zhang, Shuchang, Huang, Junkai, Man, Maoqiang, Hu, Lizhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733008/ https://www.ncbi.nlm.nih.gov/pubmed/33336085 http://dx.doi.org/10.1016/j.bbrep.2020.100869 |
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