Relationship of Telomere Length to Fat Redistribution in HIV

Persons with HIV demonstrate increased risk for aging-associated complications and have reduced telomere length (TL) compared with age-matched persons without HIV. Our data show that greater visceral fat is related to reduced TL in HIV, independent of age and smoking. Fat redistribution may be a rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Iyengar, Sanjna, Cȏté, Hélène C F, Fitch, Kathleen V, Torriani, Martin, Feldpausch, Meghan, Srinivasa, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733235/
https://www.ncbi.nlm.nih.gov/pubmed/33335933
http://dx.doi.org/10.1093/ofid/ofaa523
_version_ 1783622233065783296
author Iyengar, Sanjna
Cȏté, Hélène C F
Fitch, Kathleen V
Torriani, Martin
Feldpausch, Meghan
Srinivasa, Suman
author_facet Iyengar, Sanjna
Cȏté, Hélène C F
Fitch, Kathleen V
Torriani, Martin
Feldpausch, Meghan
Srinivasa, Suman
author_sort Iyengar, Sanjna
collection PubMed
description Persons with HIV demonstrate increased risk for aging-associated complications and have reduced telomere length (TL) compared with age-matched persons without HIV. Our data show that greater visceral fat is related to reduced TL in HIV, independent of age and smoking. Fat redistribution may be a relevant mediator of TL attrition in HIV.
format Online
Article
Text
id pubmed-7733235
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-77332352020-12-16 Relationship of Telomere Length to Fat Redistribution in HIV Iyengar, Sanjna Cȏté, Hélène C F Fitch, Kathleen V Torriani, Martin Feldpausch, Meghan Srinivasa, Suman Open Forum Infect Dis Brief Reports Persons with HIV demonstrate increased risk for aging-associated complications and have reduced telomere length (TL) compared with age-matched persons without HIV. Our data show that greater visceral fat is related to reduced TL in HIV, independent of age and smoking. Fat redistribution may be a relevant mediator of TL attrition in HIV. Oxford University Press 2020-10-27 /pmc/articles/PMC7733235/ /pubmed/33335933 http://dx.doi.org/10.1093/ofid/ofaa523 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Iyengar, Sanjna
Cȏté, Hélène C F
Fitch, Kathleen V
Torriani, Martin
Feldpausch, Meghan
Srinivasa, Suman
Relationship of Telomere Length to Fat Redistribution in HIV
title Relationship of Telomere Length to Fat Redistribution in HIV
title_full Relationship of Telomere Length to Fat Redistribution in HIV
title_fullStr Relationship of Telomere Length to Fat Redistribution in HIV
title_full_unstemmed Relationship of Telomere Length to Fat Redistribution in HIV
title_short Relationship of Telomere Length to Fat Redistribution in HIV
title_sort relationship of telomere length to fat redistribution in hiv
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733235/
https://www.ncbi.nlm.nih.gov/pubmed/33335933
http://dx.doi.org/10.1093/ofid/ofaa523
work_keys_str_mv AT iyengarsanjna relationshipoftelomerelengthtofatredistributioninhiv
AT cotehelenecf relationshipoftelomerelengthtofatredistributioninhiv
AT fitchkathleenv relationshipoftelomerelengthtofatredistributioninhiv
AT torrianimartin relationshipoftelomerelengthtofatredistributioninhiv
AT feldpauschmeghan relationshipoftelomerelengthtofatredistributioninhiv
AT srinivasasuman relationshipoftelomerelengthtofatredistributioninhiv

Ejemplares similares