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Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study
BACKGROUND: Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. METHODS: In this retrospective population-based cohort study...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733243/ https://www.ncbi.nlm.nih.gov/pubmed/33308221 http://dx.doi.org/10.1186/s12894-020-00769-1 |
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author | Amiri, Mozhdeh Heshmatollah, Sofimajidpour Esmaeilnasab, Nader Khoubi, Jamshid Ghaderi, Ebrahim Roshani, Daem |
author_facet | Amiri, Mozhdeh Heshmatollah, Sofimajidpour Esmaeilnasab, Nader Khoubi, Jamshid Ghaderi, Ebrahim Roshani, Daem |
author_sort | Amiri, Mozhdeh |
collection | PubMed |
description | BACKGROUND: Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. METHODS: In this retrospective population-based cohort study that explores the survival of patients with bladder cancer and its related factors, we first collected demographic information and medical records of 321 patients with bladder cancer through in-person and telephone interviews. Then, in the analysis phase, Kaplan–Meier method and log-rank test were used to draw the survival curve, compare the groups, and explore the effect of risk factors on the patient survival rate using Cox proportional hazards model. RESULTS: The median survival rate of patients was 63.2 (54.7–72) months and one, three and five-year survival rates were 87%, 68% and 54%, respectively. The results of multiple analyses using Cox's proportional hazards model revealed that variables of sex (male gender) (HR = 11.8, 95% CI: 0.4–100.7), more than 65 year of age (HR = 4.1, 95% CI: 0.4–11), occupation, income level, (HR = 0.4, 95% CI: 0.2–0.8), well differentiated tumor grade (HR = 3.2, 95% CI: 1.7–6) and disease stage influenced the survival rate of patients (p < 0.05). CONCLUSION: The survival rate of patients with bladder cancer in Kurdistan province is relatively low. Given the impact of the disease stage on the survival rate, adequate access to appropriate diagnostic and treatment services as well as planning for screening and early diagnosis, especially in men, can increase the survival rate of patients. |
format | Online Article Text |
id | pubmed-7733243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-77332432020-12-14 Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study Amiri, Mozhdeh Heshmatollah, Sofimajidpour Esmaeilnasab, Nader Khoubi, Jamshid Ghaderi, Ebrahim Roshani, Daem BMC Urol Research Article BACKGROUND: Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. METHODS: In this retrospective population-based cohort study that explores the survival of patients with bladder cancer and its related factors, we first collected demographic information and medical records of 321 patients with bladder cancer through in-person and telephone interviews. Then, in the analysis phase, Kaplan–Meier method and log-rank test were used to draw the survival curve, compare the groups, and explore the effect of risk factors on the patient survival rate using Cox proportional hazards model. RESULTS: The median survival rate of patients was 63.2 (54.7–72) months and one, three and five-year survival rates were 87%, 68% and 54%, respectively. The results of multiple analyses using Cox's proportional hazards model revealed that variables of sex (male gender) (HR = 11.8, 95% CI: 0.4–100.7), more than 65 year of age (HR = 4.1, 95% CI: 0.4–11), occupation, income level, (HR = 0.4, 95% CI: 0.2–0.8), well differentiated tumor grade (HR = 3.2, 95% CI: 1.7–6) and disease stage influenced the survival rate of patients (p < 0.05). CONCLUSION: The survival rate of patients with bladder cancer in Kurdistan province is relatively low. Given the impact of the disease stage on the survival rate, adequate access to appropriate diagnostic and treatment services as well as planning for screening and early diagnosis, especially in men, can increase the survival rate of patients. BioMed Central 2020-12-11 /pmc/articles/PMC7733243/ /pubmed/33308221 http://dx.doi.org/10.1186/s12894-020-00769-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Amiri, Mozhdeh Heshmatollah, Sofimajidpour Esmaeilnasab, Nader Khoubi, Jamshid Ghaderi, Ebrahim Roshani, Daem Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title_full | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title_fullStr | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title_full_unstemmed | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title_short | Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013–2018): a population-based study |
title_sort | survival rate of patients with bladder cancer and its related factors in kurdistan province (2013–2018): a population-based study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733243/ https://www.ncbi.nlm.nih.gov/pubmed/33308221 http://dx.doi.org/10.1186/s12894-020-00769-1 |
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