Transcriptional heterogeneity between primary adult grey and white matter astrocytes underlie differences in modulation of in vitro myelination

BACKGROUND: Multiple sclerosis (MS) is an inflammation-mediated demyelinating disease of the central nervous system that eventually results in secondary axonal degeneration due to remyelination failure. Successful remyelination is orchestrated by astrocytes (ASTRs) and requires sequential activation...

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Detalles Bibliográficos
Autores principales: Werkman, Inge L., Dubbelaar, Marissa L., van der Vlies, Pieter, de Boer-Bergsma, Jelkje J., Eggen, Bart J. L., Baron, Wia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733297/
https://www.ncbi.nlm.nih.gov/pubmed/33308248
http://dx.doi.org/10.1186/s12974-020-02045-3

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