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Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice

PURPOSE: Diallyl sulfide (DAS), one of the organo-sulfur secondary metabolites in garlic, has been shown to inhibit the proliferation of cancer cells. The present study aimed to evaluate the mechanism of DAS in the prevention of benzo[a]pyrene (BaP)-induced lung cancer in a murine model. MATERIALS A...

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Detalles Bibliográficos
Autores principales: Khan, Arif, Alhumaydhi, Fahad A, Alwashmi, Ameen S S, Allemailem, Khaled S, Alsahli, Mohammed A, Alrumaihi, Faris A, Almatroudi, Ahmad, Mobark, Mugahid A, Mousa, Ayman, Khan, Masood A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733419/
https://www.ncbi.nlm.nih.gov/pubmed/33324084
http://dx.doi.org/10.2147/JIR.S284279