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Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015

INTRODUCTION: Studies have shown that pneumococcal disease significantly increases morbidity and mortality rates in children 5 years old and under. These infections constitute the main cause of preventable deaths in the world, considering the availability of vaccination. Considering that Ecuador is...

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Autores principales: Jimbo-Sotomayor, Ruth, Armijos-Acurio, Luciana, Proaño-Espinosa, José, Segarra-Galarza, Katy, Sánchez-Choez, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733426/
https://www.ncbi.nlm.nih.gov/pubmed/33343162
http://dx.doi.org/10.4103/jgid.jgid_125_19
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author Jimbo-Sotomayor, Ruth
Armijos-Acurio, Luciana
Proaño-Espinosa, José
Segarra-Galarza, Katy
Sánchez-Choez, Xavier
author_facet Jimbo-Sotomayor, Ruth
Armijos-Acurio, Luciana
Proaño-Espinosa, José
Segarra-Galarza, Katy
Sánchez-Choez, Xavier
author_sort Jimbo-Sotomayor, Ruth
collection PubMed
description INTRODUCTION: Studies have shown that pneumococcal disease significantly increases morbidity and mortality rates in children 5 years old and under. These infections constitute the main cause of preventable deaths in the world, considering the availability of vaccination. Considering that Ecuador is in a high incidence region, despite the introduction of the vaccine, this study aims to describe the burden of hospitalized pneumococcal disease and related mortality in our country between 2005 and 2015, to help decision-making processes for the health authorities. METHODS: This cross-sectional study analyzes morbidity, mortality, and the situation in Ecuador caused by pneumococcal disease in children 5 years old and under between 2005 and 2015 using national databases. RESULTS: A total of 163,852 cases of children 5 years old and under were reported to have been hospitalized due to pneumococcal-related diseases. Males comprised 54.7% of the cases and females 45.3%. In 36% of the cases, the patients were 1 year old or under. The mortality rate due to pneumococcal disease in Ecuador in children aged 5 and under decreased in 48% during 2005–2015. CONCLUSION: The decrease in mortality can be related to the introduction of the vaccine and an increase in access to health care by the general population in the country. It is important to study the specific impact of the vaccine in the reduction of morbidity and mortality of children in Ecuador.
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spelling pubmed-77334262020-12-18 Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015 Jimbo-Sotomayor, Ruth Armijos-Acurio, Luciana Proaño-Espinosa, José Segarra-Galarza, Katy Sánchez-Choez, Xavier J Glob Infect Dis Original Article INTRODUCTION: Studies have shown that pneumococcal disease significantly increases morbidity and mortality rates in children 5 years old and under. These infections constitute the main cause of preventable deaths in the world, considering the availability of vaccination. Considering that Ecuador is in a high incidence region, despite the introduction of the vaccine, this study aims to describe the burden of hospitalized pneumococcal disease and related mortality in our country between 2005 and 2015, to help decision-making processes for the health authorities. METHODS: This cross-sectional study analyzes morbidity, mortality, and the situation in Ecuador caused by pneumococcal disease in children 5 years old and under between 2005 and 2015 using national databases. RESULTS: A total of 163,852 cases of children 5 years old and under were reported to have been hospitalized due to pneumococcal-related diseases. Males comprised 54.7% of the cases and females 45.3%. In 36% of the cases, the patients were 1 year old or under. The mortality rate due to pneumococcal disease in Ecuador in children aged 5 and under decreased in 48% during 2005–2015. CONCLUSION: The decrease in mortality can be related to the introduction of the vaccine and an increase in access to health care by the general population in the country. It is important to study the specific impact of the vaccine in the reduction of morbidity and mortality of children in Ecuador. Wolters Kluwer - Medknow 2020-08-29 /pmc/articles/PMC7733426/ /pubmed/33343162 http://dx.doi.org/10.4103/jgid.jgid_125_19 Text en Copyright: © 2020 Journal of Global Infectious Diseases http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jimbo-Sotomayor, Ruth
Armijos-Acurio, Luciana
Proaño-Espinosa, José
Segarra-Galarza, Katy
Sánchez-Choez, Xavier
Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title_full Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title_fullStr Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title_full_unstemmed Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title_short Morbidity and Mortality Due to Pneumococcal Disease in Children in Ecuador from 2005 to 2015
title_sort morbidity and mortality due to pneumococcal disease in children in ecuador from 2005 to 2015
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733426/
https://www.ncbi.nlm.nih.gov/pubmed/33343162
http://dx.doi.org/10.4103/jgid.jgid_125_19
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