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Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea

Neurons of the medial olivary complex inhibit cochlear hair cells through the activation of α9α10-containing nicotinic acetylcholine receptors (nAChRs). Efforts to study the localization of these proteins have been hampered by the absence of reliable antibodies. To overcome this obstacle, CRISPR-Cas...

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Detalles Bibliográficos
Autores principales: Vyas, Pankhuri, Wood, Megan Beers, Zhang, Yuanyuan, Goldring, Adam C., Chakir, Fatima-Zahra, Fuchs, Paul Albert, Hiel, Hakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733449/
https://www.ncbi.nlm.nih.gov/pubmed/33311584
http://dx.doi.org/10.1038/s41598-020-78380-5