Three-dimensional in situ morphometrics of Mycobacterium tuberculosis infection within lesions by optical mesoscopy and novel acid-fast staining

Tuberculosis (TB) preclinical testing relies on in vivo models including the mouse aerosol challenge model. The only method of determining colony morphometrics of TB infection in a tissue in situ is two-dimensional (2D) histopathology. 2D measurements consider heterogeneity within a single observabl...

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Detalles Bibliográficos
Autores principales: Francis, Robert J., Robb, Gillian, McCann, Lee, Khatri, Bhagwati, Keeble, James, Dagg, Belinda, Amos, Brad, Salguero, Francisco J., Ho, Mei Mei, Bullen, Anwen, McConnell, Gail, MacLellan-Gibson, Kirsty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733456/
https://www.ncbi.nlm.nih.gov/pubmed/33311596
http://dx.doi.org/10.1038/s41598-020-78640-4

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