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Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers
While the majority of cells contain a single nucleus, cell types such as trophoblasts, osteoclasts, and skeletal myofibers require multinucleation. One advantage of multinucleation can be the assignment of distinct functions to different nuclei, but comprehensive interrogation of transcriptional het...
Autores principales: | Petrany, Michael J., Swoboda, Casey O., Sun, Chengyi, Chetal, Kashish, Chen, Xiaoting, Weirauch, Matthew T., Salomonis, Nathan, Millay, Douglas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733460/ https://www.ncbi.nlm.nih.gov/pubmed/33311464 http://dx.doi.org/10.1038/s41467-020-20063-w |
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